DarthYoshiBoy

So this is neat. Potentially life changing for some type 2 diabetics, but that depends because some t2 diabetics are not failing to make enough insulin, they’re just no longer sensitive to it at a level that makes it functional for them. I suppose it’s possible that this therapy could cause them to grow enough islet β cells to overcome their lack of sensitivity, but (and I’m a type 1, not a type 2, so maybe my info is incorrect here) that lack of sensitivity can grow with further exposure to insulin making this a stop-gap at best for those cases absent other therapies.

…and with all of that said, being able to regrow islet β cells has never really been the problem for type 1 diabetes. You can regrow all the islet β cells you’d like and it’s not going to cure the underlying immune disease that has caused your immune system to kill off all of your islet β cells to begin with. Unless you can figure out why t1 diabetes causes one’s own immune system to go psycho killer on their islet β cells, you’ve done nothing to “cure” diabetes. Without being able to suppress that impulse for your immune system to murder your own cells, any ability to replace the islet β cells is going to be temporary at best, and probably a waste on the whole.

My brother in law is a “cured” type 1 diabetic, by virtue of his having had a kidney replacement and being on immune suppressing drugs for that. Since they were already replacing the kidney and he was going to have to take immune system suppression medications for that, they also just replaced his pancreas at the same time and the suppression of his immune system has allowed the new pancreas to thrive and continue to make insulin. Easy-peasy. The only trade-off is that he is super immunocompromised and can be killed by common colds, so not a great strategy in general.

I accidentally misclicked this article and reported it as spam while I was trying to report some prescription drug spam. Hopefully it’s not adversely affected. I wish there was an Undo on that action.

The Nissan Connect stuff doesn’t work anymore for any of the 2016 Leafs, they used a form of cell service that is no longer in operation.

I swapped a nice Kenwood head unit into my Leaf for a couple hundred dollars. It maintains the backup camera, steering wheel controls, and the built in USB port while offering a larger screen and touch screen controls for Android Auto or Apple Car Play if you want them. It’s awesome and I highly recommend it for anyone who wants a short range commuter car.

I assume this is a Stargate thing and that there aren’t actually that many Skeptical Guide podcasts out there.

I haven’t got any dog in the Stargate fight, I’ve seen the original movie (good) and watched the Richard Dean Anderson TV series (better than the movie) for a while before it just fell off my radar? I’ll take your word for it that Stargate Universe is the lesser of the Stargate properties.

SGU in my comment obviously is referring to the Skeptics Guide to the Universe aka, the linked podcast.

I’ve never listened to Rogan*, but I think https://www.theskepticsguide.org/podcasts does an excellent job of talking about current news and science items in an easily digestible format that mostly avoids bullshit while probably filling the same gee-whiz niche that people expect from Rogan? It’s a panel, so not a single muscular male host, but I think if your sibling is pursuing Rogan because they think it’s helping expose them to new interesting ideas, SGU is a vastly superior route to that end.

*I actually think my only Rogan exposure has been the SGU talking about how he more or less just believes the last thing anyone told him, whatever that might be, which seems… less good?

https://www.patreon.com/Orioto

Might just be a me thing, but this guy puts out a new wallpaper almost every week and they’re all amazing. The higher tiers allow you to participate in choosing the next wallpaper, but they’re mostly for 1080p, 1440p, and 2160p. Buying in once gets you the whole lot of everything he’s done until now.

At this point they’re only wagging their fingers to make it appear as though they’re considering regulation.

Again, it’s disingenuous to claim that their pragmatism in the face of unreasonable actors is the same as being the unreasonable actors. What are the left supposed to do? Pull a Trump and pretend that the laws and systems that make our country don’t exist and just say that what they want is law and ignore that half the country is electing morons who will fight them at every turn? That’s not how it works and frankly I wouldn’t want it to work that way because it’s just incredibly dangerous. They’re trying to work within a system where the right has learned they can con half the country into believing they’re doing their job while they sit back and do their damnedest to ensure that the government doesn’t function at all because that’s the only way that conservatives can stop progress at this point with their platforms being as unpopular as they are.

The left is definitely more open to considering regulation. It’s not even close. The right thinks that regulation is a four letter word and they’re generally not a fan of those either. It’s disingenuous to both sides everything. Much of the time where the left allows a carveout for vampirism, it’s because it’s the best compromise they can mange to a given end given that the right is out there swabbing their throats and getting all hot and bothered waiting for daddy Drac to come and give it to them, not because it’s their preference that we allow unfettered late-stage capitalism to destroy lives. Again, it’s disingenuous to claim that their pragmatism in the face of unreasonable actors is the same as being the unreasonable actors (and I am well aware that there are exceptions that prove the rule on both sides of the isle, so 🤷‍♂️)

…and lest anyone think that this problem isn’t solved with government regulation, I invite you to look at the medication situation in nearly any other country in the world where by and large they are not afraid of regulation for the same drug companies that are fucking us sideways and see how much cheaper and better their access to medications is solely because they’re willing to support that maybe there is a greater public good than shareholder profits.

This is of course their MO. They were making Insulin for pennies per vial for years and selling it for hundreds of dollars per. It’s funny how they’re allowed to keep doing this to us and they probably always will because the US right thinks the immoral thing is not letting vampires have a suck whenever they want it. Obesity and Diabetes are a couple of the largest killers around, to say nothing of the losses in Quality of Life they cause. It’s just insane that we refuse to regulate prices for drugs that would relieve immeasurable suffering and death because CEOs gotta have a nicer Yacht or how is life any fair?

It’s a pretty great game. Really good music and one of those gameplay loops that is easy to pick up and difficult to master. If you like Tetris and the like, Lumines is worth your attention.

Lumines

My suggestion would be to reframe your thesis. Rather than consuming content, change your perspective to one where you are appreciating art.

The world is vast and full of amazing things, you don’t need to feel like you’re wasting time when you dedicate that time to appreciating art that you love. There are books, games, movies, short form video essays, podcasts, and all sorts of things that are real expressions of the human experience from different angles, which is what art is, and there’s nothing wrong with appreciating that art, learning something from it, and growing your understanding.

Unless you’re harming yourself or others by enjoying the art you enjoy, just keep on doing it.

That said, if you really want something else, gaming is (IMO) a great way to spend some time, tabletop or video. Learning a programming language is another one and can lead to very fulfilling paths where you can make things that you enjoy and easily share them with others.

I’ll be honest, I could sometimes find a helpful answer there, but for about the last 2 years it has taken 3 reloads of a page at least before it actually loads any content, otherwise it just sits there at a plain white page showing their logo and I usually give up rather than try to get lucky with a page actually loading.

My favorite Libertarian society experiment. I mean, it’s the only one that I’m aware of, but that it ended about as well as you’d expect is just fantastic.

I’m not the original owner of my Mazda either, I had the upgrade done well after the original sale of that vehicle. I had also looked into the software modding scene but decided that an official upgrade costing only $400 wasn’t worth the potential headaches of hacky homebrew updates I had to service myself.

My Mazda is a 2016 CX-5. It was a limited option in 2016, but it was an option, and it only cost me $400 to purchase the upgraded head unit and have it installed by my Mazda dealership. I don’t know what model yours is, but 2016 is the year that you can actually look into the option depending. It was going to run me more than $400 to do my own AA solution with the risks of losing the steering wheel or knob controls, so $400 for the upgrade that retains all of that without any hacky workarounds was a godsend.

Your Mastodon data is already an open book to Meta if they care to have it. The protocol is open, they could already be black-ops scooping up everything that’s fit to federate without turning on Threads federation, so them doing that really changes nothing. And what I mean by that is that they could already have set up unknown instances to leech whatever data they want out of the Fediverse, which instances masquerade as normal mom and pop installs just federating and sucking up everything without bringing anything back to the table. There’s literally nothing stopping them from leeching everything out of the Fediverse at any time other than people being better at detecting their activity (and actively thwarting that activity) than Meta is at keeping it off the radar.

In this case they’re making it so that I might have a chance to follow and interact with people already in the Meta/Instagram/Threads atmosphere without having to convince those people to leave the confines of what they’re comfortable with and find a Mastodon instance to sign up for. Maybe they’ll be more comfortable with leaving Meta after dipping their toes in the open spec?

How is that not a win? If Meta/Threads decide that they want to fracture the protocol and go do their own thing later, so what? We’ll go right back to where we were before they brought their users into the Fediverse. If people decide that they value the Threads extras/connections more than they value the purity of the ActivityPub protocol then maybe Meta is actually providing something that matters and we’ve lost by not supplying that need before the corporate interest figured out that it existed. In that case we’ll deserve the death that causes in use of the open spec, but the open spec will still be there and people who want to do their own thing with it can’t be stopped now. The code to run an open ActivityPub Mastodon instance is already out there and it’s impossible to take it back now.

Everyone is out here decrying this as a subtle takeover of the Fediverse by Meta, but did Facebook “takeover” the HTTP spec when they started operating facebook (dot) com on the world wide web over the HTTP protocol? It’s an insane assertion. I’ve been running my own opensource web servers since well before Facebook was a thing and I’ve continued to do so despite most people opting to depend on a mega-corp to be steward of their online presence. That Meta has a very successful and popular website that I’ve never been a fan of has never impacted my ability to use the open protocol they operate on to continue doing my own thing. The same thing will be true here.

It really seems like people are just upset that Threads might bring ActivityPub to the mainstream and force them to contend with the realization that a diaspora of open spec implementations already lost the war to Meta/Facebook. We had that once before. It was called the World Wide Web and you could go and find forums, fan pages, company websites, and everything else back then that has since moved to Facebook (or other content aggregator sites) because people value the network effects and homogenization more than they care about one big company being in charge of it all. (…and not to belabor the point, but most of that stuff is still out there, it’s just waned in popularity because the network effects are not there.) Here we are with a chance to try and break things out again and people are seemingly worried that we can’t if we let the Meta users in? Maybe they’re right, maybe it’s impossible to achieve victory here, but gatekeeping the standard and enacting some purity test for which providers are allowed on the protocol isn’t going to tip the scales in favor of the open standards implementation.

If the protocol is truly open, then how can a corporation embracing it be a danger? We’re all free to adopt any changes or not at any point in the journey so it’s impossible to lose, you’re free to keep doing your own thing any way you look at it. Tell me how any of this is untrue.

TL;DR: Threads coming to the Fediverse is a good thing. It’ll make it possible to expand the network effects of an open protocol far faster and more than any amount of Fedinerds proselyting the gospel of ActivityPub ever will. The only thing that is at risk of being lost is that we’ll refuse to adapt to what end users want fast enough to keep a large corporation from bending the spec to their ends. Which loss again only means that you’d be cutting yourself off from those who WANT to embrace the revised spec by not adopting those changes yourself. That option (to just not adopt changes to the spec) can’t be taken away from you in the future, so worrying is only warranted if you feel like your ideal ActivityPub implementation can’t win out in the marketplace of ideas and that you’re owed that victory even if others are able to expand it in ways that people actually want to use enough to dismiss whatever downsides it contains.

I’ve a Mazda with Android Auto that doesn’t use a touch screen. It’s all controlled with a joystick/knob/button setup that is actually really nice. I wish my Nissan had a similar setup all the time.

In the Mazda I know how many physical interactions will get me the result I want, it takes barely more than a glance at the screen to know what’s up. With the touch interface I have to put my eyes on the screen to confirm that the car didn’t bounce when I went to tap a “button” and/or confirm that the tap was actually registered. I know that GM has to know that Android Auto supports non touchscreen interactions. If they’re concerned about how unsafe touchscreens are, just add a knob to the center console that doubles as a 4-way joystick like Mazda has and all those concerns go away. It’s really that simple and it IS miles better than using touch for everything.

Megatron

• Not religious
• Not a surname
• Not a place
• Doesn’t rhyme with Aden
• Is a sci-fi name

The only issue little Megatron will ever face in life is the possibility of an Optimus Prime showing up some day, he’s otherwise right on the path to world domination, and who couldn’t love that? 😉

I look back at the PS2’s library (to be fair, it was enormous even for its own time) and everything on the Switch feels tiny in comparison.

https://en.wikipedia.org/wiki/List_of_PlayStation_2_games_(A%E2%80%93K) vs. https://en.wikipedia.org/wiki/List_of_Nintendo_Switch_games

If there aren’t legit more Nintendo Switch games than there were PS2 games right now, I imagine that the Switch will just trample the PS2 before its end.